Anchorage Independent

Views Updated: Dec 15, 2025

Abbreviation

Pronunciation

/ˈæŋkərɪʤ ˌɪndɪˈpɛndənt/

The H 1 host NB 324 K cells were also tested using the anchorage independent assay and the tumour formation in nude mice. Both of the assays gave negative results.
The characteristics of the cellular biology and the malignant transformation phenotype of cells were identified through observing serum resistance, anchorage independent growth, etc.
It indicated that the abnormal expression of cyclinE was related to malignant proliferation and anchorage independent growth of human breast cancer cells.
The cellular telomerase activities were analyzed with TRAP The immortalized cells were incubated in a soft-agarose medium containing 10 % FCS and the anchorage independent growth abilities of the tested cell lines were evaluated.
The experiment performed on the transfectant cells showed that the growth rate of these cells was significantly slowed, and the properties of anchorage independent growth and tumorigenicity in nude mice was lost.

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