G protein

Views Updated: Dec 15, 2025

Abbreviation

Pronunciation

/ʤi ˈproʊˌtin/

Effect of G Protein βγ Subunits on Phosphorylation of M2 Receptor
As a super-family of membrane receptor, G protein(GP) play various functions in the body.
Even though this receptor can still bind vasopressin at its external surface, the receptor cannot activate the G protein(GP) and thus cannot pass the signal downstream to the effector.
How, the scientists wanted to know, is the G protein(GP) targeted so quickly and precisely to activate the channel?
After being activated by the receptor, the G protein(GP) changes shape, opening the ion channel.

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