GPIRS Views 5 meanings found GPIRS describes a Global Positioning/Inertial Reference System used in navigation and aerospace, while the same acronym also appears in inventory management and psychotherapy rating tools. Miscellaneous Global Position Inertial Reference System Governmental Global Positioning/Inertial Reference System Gas Production Inquiry and Report System Academic & Science Group Psychotherapy Intervention Rating Scale Computing Global Prototype Inventory Requisitioning and Scheduling