hypercalcaemia

Views Updated: Dec 15, 2025

Abbreviation

Pronunciation

/ˌhaɪpərkælˈsiːmiə/

Hypercalcaemia and bone metastases of malignancy are frequently diseases in advanced cancer patients, it threatens patients ' life and brings the patients with great pain.
Multiple myeloma is a malignant plasma cell disorder. And it is characterized by heterogeneous anemia, bone disease, renal impairment, hypercalcaemia(HC) and infections due to patchy accumulation of malignant plasma cells within the marrow microenvironment.
PURPOSE To evaluate the efficacy, convenient dosage and side effect of pamidronate for metastatic bone pain and hypercalcaemia(HC) of malignancy.
The effective rate of moving ability improvement was 84.4 %. After treatment, nine patients with hypercalcaemia(HC) whose serum calcium reduced to normal in 77.78 %.
Bisphosphonates with a imidazole ring have higher affinity for bone mineral, and zoledronate is just a good example which is extensively used clinically for the treatment of patients with tumour-induced, hypercalcaemia(HC) and osteolytic bone metastases.

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