Mantle Cell Lymphoma
Key Facts
Abbreviation
MCL
Pronunciation
/ˈmæntəl sɛl lɪmˈfoʊmə/
Category
Medical
Related Field
Oncology
Examples in Context
- Clinical analysis and diagnosis of mantle cell lymphoma presented as lympho-proliferative disease
- Objective To investigate the feasibility of detecting cyclin D1 protein expression and t ( 11; 14 ) chromosomal translocation in paraffin-embedded tissues and its diagnostic and differential diagnostic significance for mantle cell lymphoma ( MCL ).
- Camclusions : It is considered as a distinctive peripheral B-cell lymphoma, and should distinguish with hairy cell leukemia, splenic mantle cell lymphoma, splenic lymphoma with villous lymphoma and B mucosa-associated lymphoma.
- Methods : A semi nested PCR method to amplify bcl 1 / IgH gene rearrangement in DNA from fresh frozen lymphonode specimen was established. Twenty eight cases of mantle cell lymphoma were analyzed for the presence of bcl 1 / IgH gene rearrangement.
- Insect bite-like reaction associated with mantle cell lymphoma : A report of two cases and review of the literature
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