MLSE Views 9 meanings found MLSE is best known as the abbreviation for Toronto’s Maple Leaf Sports & Entertainment, a major multi‑team ownership group, though it is occasionally used humorously for other sports ventures. Miscellaneous Maximum Likelihood Sequence Estimation Microsoft Licensing Sales Expert Makes Losing Seem Easy Business Maple Leaf Sports and Entertainment (Toronto multi-ownership Sports Multiple Losing Sports Enterprises Maple Leaf Sports Entertainment Maple Leafs Sports and Entertainment Maple Leaf Sports and Entertainment Maple Leafs Sports Entertainment