Volume of Distribution

Views Updated: Dec 15, 2025

Abbreviation

Pronunciation

/ˈvɑljum əv ˌdɪstrəˈbjuʃən/

Heparin has a larger volume of distribution and a more rapid plasma clearance in infants than in adults.
The apparent volume of distribution and the unbound fraction in plasma are the most widely used parameters for drug distribution.
The apparent volume of distribution is the amount of fluid that would be required to contain the drug in the body at the same concentration as in the blood or plasma.
In response to this problem, the article establishes a mathematical model on the basis of the third-party logistics to calculate the reasonable holding volume of distribution vehicles.
With the third-party distribution resources, the reasonable holding volume of distribution vehicles calculated by this model can fully satisfy the fluctuant demand, reduce the cost of the vehicles purchase and achieve the minimum total cost of distribution.

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