X- Chromosome Inactivation
Key Facts
Abbreviation
XCI
Pronunciation
/ɛks ˈkroʊməˌzoʊm ˌɪˌnæktɪˈveɪʃən/
Category
Medical
Related Field
Human Genome
Examples in Context
- Skewed X Chromosome Inactivation and Imprinted / X-linked Gene Expression in Human Embryonic Stem Cells
- Independent clonal origin of multiple uterine leiomyomas that was determined by X chromosome inactivation and microsatellite analysis
- It has profound effects on biological processes in mammals, including gene expression and developmental regulation, differentiation, genomic imprinting, X chromosome inactivation and biological defense etc..
- Methylation and demethylation of DNA are the complementary processes of epigenetic regulation. Methylation and demethylation influence a diverse array of cellular activities, including X chromosome inactivation, genomic imprinting, chromatin modification, and the silencing of endogenous genes.
- Although recent experiments have demonstrated normal reprogramming of telomere length and X chromosome inactivation, epigenetic information established during gametogenesis, such as gametic imprints, cannot be restored after nuclear transfer.