Yeast Artificial Chromosome

Views Updated: Dec 15, 2025

Key Facts

Abbreviation
YAC
Pronunciation
/jist ˌɑrtəˈfɪʃəl ˈkroʊməˌzoʊm/
Category
Medical
Related Field
Human Genome

Examples in Context

  1. Yeast Artificial Chromosome(YAC) ( YAC ) techniques play an important role in the analysis of human genome and the isolation and cloning of disease related genes.
  2. Moreover, yeast artificial chromosome ( YAC ) cloning and site-specific mutation techniques can be combined with transgenic technique to investigate the developmental gene regulation of large genes ( clusters ) with mutations in different sites.
  3. Centromere, telomere and origins of replication are important elements to maintain the mitotic stability of chromosome. The Yeast Artificial Chromosome(YAC) ( YAC ) was firstly built in 1983 triumphantly by using these elements of yeast.
  4. Reconstruction of large genomic segment coding for human immunoglobulin κ chain by meiotic homologous recombination of yeast artificial chromosome
  5. It have been reported that the 210 kb yeast artificial chromosome ( YAC ) including the human a - lactalbumin gene could direct the transgene to express in a position-independent manner, therefore is an excellent expression vector to produce transgenic animal bioreactors.

Other meanings of YAC